You have a whole generation of manga fans and who are familiar with DC characters through the DCAU. One of the reasons the YA market is booming is because teen girls and women are more than willing to buy stuff. Just stop making the environment hostile to them, give some female characters series/stronger roles (seriously, do a "Stargirl & Cyclone have wacky awesome adventures" series and market it properly to girls the characters' ages and you'd do well) and you'd make loads on money.

It occurs to me that DC's Enchantress, as characterized and costumed in the Silver Age, would be a natural to reinvent as a manga-style Magical Girl.